发布时间：2008.6
摘要
这份报告分析了全球合同研究外包市场。报告中分析的主要细分行业包含药物发现和临床研究。报告分别综合分析了美国，欧洲，亚洲和全球其他地区的市场并且介绍了全球219家公司。
This report analyzes the worldwide markets for Contract Research Outsourcing in Millions of US$. The major Service segments analyzed are Drug Discovery, and Clinical Research. The report provides separate comprehensive analytics for the US, Europe, Asia, and Rest of World. Annual forecasts are provided for each region for the period of 2000 through 2015. The report profiles 219 companies including many key and niche players worldwide such as Criterium, Inc., Covance, Inc., Encorium Group, Inc., ICON PLC, Kendle, Life Sciences Research, Inc., MDS Pharma Services, MPI Research, Omnicare Clinical Research, Parexel International Corporation, PharmaNet Development Group, Inc., PRA International, Pharmaceutical Product Development, Inc., Quintiles Transnational Corporation, WIL Research Laboratories, LLC, Bio Analytical Research Corporation, Calvert Laboratories, Inc., CentraLabS Clinical Research, Charles River Laboratories, Inc., Huntingdon Life Sciences Research, Inc., Laboratory Corporation of America?Holdings, Lab Research, Inc., Pacific Biometrics, Inc., Perry Scientific, Inc., Quest Diagnostics, Inc., SNBL USA, Ltd., DaVita Clinical Inc., nTouch Research Corporation, PharmaTrials, Inc., Radiant Research, Inc., and Research Solutions, LLC. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
目录及图表
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 3
Study Reliability and Reporting Limitations...I-1
Disclaimers...I-2
Data Interpretation & Reporting Level...I-2
Quantitative Techniques & Analytics...I-3
Product Definitions and Scope of Study...I-3
II. EXECUTIVE SUMMARY 43
1. Industry Overview...II-1 2
Background...II-1
Growth and Transformation of CRO Industry...II-1
Table 1: Number of Clinical Trials Worldwide (2000-2007) (includes corresponding Graph/Chart)...II-1 1
Table 2: Percentage Breakup of Number of Pipeline Drugs Worldwide by Phase- Preclinical, Phase I, Phase II, Phase III and Phase IV (2007) (includes corresponding Graph/Chart)...II-2
Advantages of CRO for Pharmaceutical Companies...II-2
Advantages of CRO for Clinical Research Organizations...II-2 1
2. Industry Potential...II-3 7
Outlook...II-3
Competition Potential...II-3 1
Table 3: Percentage Breakup of Life Sciences Revenues (FY 2007) of Major Players by Service Type- Preclinical, Phase I, Phase IIA, Phase IIB, Phase III, Phase IIIb/IV, Central Lab, Bioanalytical and Others...II-4
Table 4: Global CRO Market (2007): Number of CROs by Service Type- Phase I, Phase I-IV, Data Management Services (DMS), Regulatory Affairs, Quality Analysis (QA), Preclinical /Toxicology and Lab Analysis (includes corresponding Graph/Chart)...II-4 1
Table 5: Global Pre-clinical CRO Market (2007): Percentage Breakup of Market Share Based on Revenues for Charles River Labs, Covance, Life Science Research, MPI Research, SNBL USA, WIL Research Labs, MDS, LAB Research and Others (includes corresponding Graph/Chart)...II-5
Table 6: Leading Biotechnology and Pharmaceutical Research Companies Worldwide ?Ranked by Year 2006 Revenues in US$ Million (includes corresponding Graph/Chart)...II-5 1
Regional Potential...II-6
The United States...II-6
Western Europe...II-6
Central and Eastern Europe...II-6
Asia-Pacific ...II-6
China ...II-6 1
India ...II-7
Latin America...II-7
Service Potential...II-7 1
Pre-Clinical Segment Gains Momentum...II-8
Clinical Research ?Encouraging Factors at Various Phases...II-8
Phase I ...II-8
Phase II...II-8
Phase III ...II-8
Phase IV...II-8
Research & Development Potential...II-8 1
Table 7: Percentage Breakup of Global R&D Spending by Region (2008E) (includes corresponding Graph/Chart)...II-9
Table 8: Percentage Breakup of Global R&D Spending by Market (2005-2010) (includes corresponding Graph/Chart)...II-9
Role of Technology in R&D...II-9 1
3. Market Dynamics...II-10 8
Challenges Faced by Contract Research Organizations...II-10
On-shore versus Offshore CRO Business...II-10
Cutthroat Competition Among CROs...II-10
Management of Production Capacities...II-10
Management of Clinical Investigation...II-10
Cost Containment...II-10
Safety Concerns on Clinical Trials...II-10 1
Pipeline Blocks...II-11
Strategies and Tactical Programs for CROs...II-11
Survival Strategies in Mature CRO Markets...II-11
Exit from the Industry...II-11
Expand Scale...II-11
Capture Niche Segments...II-11
Expand Geographically...II-11
Strategies to Tap Opportunities in Growing Markets...II-11 1
Mobilize Funds...II-12
Expand Other Services...II-12
Upgrade Technological and Knowledge Base...II-12
Form Sub-Contracts or Regional Alliances...II-12
Asia ?Hub for Contract Research Outsourcing...II-12
Overview...II-12
Market Potential...II-12
Activity Perspective...II-12
Cost-Efficiency in Research and Development...II-12 1
World-Class Clinical Trials...II-13
Regional Perspective...II-13
China...II-13
Congenial Business Environment...II-13
Compliance with Global CRO Standards...II-13
Return of Skilled Human Resources...II-13 1
Availability of Large Genetic Population...II-14
Cost Advantages...II-14
India...II-14
Large Talent Pool of Human Resources...II-14
Increased Regulatory Compliance...II-14
Rich Genetic Diversity...II-14
Cost-Savings and World-Class Quality...II-14 1
Table 9: Cost of Conducting Clinical Trials: India Vs US (In US$ Million) (includes corresponding Graph/Chart)...II-15
Challenges in Outsourcing...II-15
China...II-15
Regulatory Hurdles...II-15
Limited Funding Resources...II-15
Demand War for Talented Personnel...II-15
Teething problems...II-15 1
Cultural and Language Difficulties...II-16
India...II-16
Restrictions on Clinical Trials...II-16
Lack of Standardization...II-16
Advantage India ?hot spot for R&D investment...II-16
Subject-compliance in major therapeutic areas...II-16
Reliable Data Generation and Management...II-16
Improved Base of Medical Infrastructure...II-16
Strong Combination of CMOs and CROs...II-16
Reverse-engineering Capabilities...II-16 1
Market Trends...II-17
Biotech Leads in CRO...II-17 1
4. Recent Industry Activity...II-18 8
India抯 Jubilant Organosys to Takeover Draxis Health...II-18
Shasun to Establish Process Development Unit in US...II-18
Quintiles to Open Second Clinical Research Office in Wilmington...II-18
LabCorp to Acquire Tandem Labs...II-18
Shasun to Establish Process Development Unit in US...II-18 1
MDS Pharma Expands in Latin America...II-19
Iris Pharma and Clirophtha Merge to Form New Iris Pharma...II-19
PPD to Acquire InnoPharm...II-19
KCR Acquires DUX Consuling...II-19
Cetero Research Acquires DGD Research...II-19 1
Jubilant Organosys Acquires Hollister- Stier Laboratories ...II-20
Shasun Acquires Rhodia Pharma Plants ...II-20
Ocimum Biosolutions Acquires Gene Logic抯 Genomics Business...II-20
Innovative Medical Device Sourcing Acquires Frontier BioMedical LLC...II-20
UK-Based Premier Research Group PLC Acquires ARS, Inc....II-20
AAIPharma, Inc. Acquires Instituto de Pesquisa Cl韓ica de S鉶 Paulo Ltda...II-20 1
Covance to Renovate New Drug Development Facility in Virginia...II-21
Covance Expands and Reshuffles Research Clinic...II-21
Perceptive Informatics Alliance To Enhance Clinical Supply Chain Forecasting and
Management...II-21
Genstar Capital Acquires PRA International...II-21
Covalent Acquires Remedium Oy and Changes Name to Encorium...II-21 1
Quintiles Enters Into a New Alliance with Washington County Hospital...II-22
Kendle Expands in US and Europe...II-22
Criterium Opens Two New Offices in Russia and Israel...II-22
Premier Research Acquires Two Companies to Expand Product Offerings...II-22
Averion Divests Staffing Services Segment...II-22
Chiltern Acquires CTMS...II-22
Quintiles Acquires Bio-Trials...II-22 1
Parexel Acquires Apex International Clinical Research...II-23
Charles River Forms Joint Venture with BioExplorer...II-23
PAREXEL Opens New Location In India...II-23
Avesthagen and Manipal Accunova Collaborate...II-23 1
Matrix and ethica Clinical Research Form ethicamatrix...II-24
Covance Opens Nutritional Chemistry Laboratory in Singapore...II-24
MDS Pharma to Expand in European Market...II-24
Vita Nova Acquires Sedoc...II-24
Averion Acquires Hesperion...II-24
Averion and BIOCANCER Form Strategic Alliance...II-24
AstraZeneca Opens First CPU to Enhance Clinical Research in China...II-24 1
AstraZeneca Acquires Biologics Manufacturing Facility...II-25
AstraZeneca Inaugurates Global Process R&D Lab in Bangalore...II-25 1
5. Focus on Key Players...II-26 9 $700
Contract Research Organizations...II-26
Criterium, Inc. (US)...II-26
Covance, Inc. (US)...II-26
Encorium Group, Inc. (US)...II-26
ICON PLC (Ireland)...II-26 1
Kendle (US)...II-27
Life Sciences Research, Inc. (US)...II-27
MDS Pharma Services (US)...II-27
MPI Research (US)...II-27 1
Omnicare Clinical Research (US)...II-28
Parexel International Corporation (US)...II-28
PharmaNet Development Group, Inc. (US)...II-28 1
PRA International (US)...II-29
Pharmaceutical Product Development, Inc. (US)...II-29
Quintiles Transnational Corporation (US)...II-29
WIL Research Laboratories, LLC (US)...II-29 1
Preclinical Laboratories...II-30
Bio Analytical Research Corporation (US)...II-30
Calvert Laboratories, Inc. (US)...II-30
CentraLabS Clinical Research (US)...II-30
Charles River Laboratories, Inc. (US)...II-30
Huntingdon Life Sciences Research, Inc. (UK)...II-30 1
Laboratory Corporation of America?Holdings (US)...II-31
Lab Research, Inc. (Canada)...II-31
Pacific Biometrics, Inc. (US)...II-31 1
Perry Scientific, Inc. (US)...II-32
Quest Diagnostics, Inc. (US)...II-32
SNBL USA, Ltd. (US)...II-32 1
Site Management Organizations...II-33
DaVita Clinical Research (US)...II-33
nTouch Research Corporation (US)...II-33
PharmaTrials, Inc. (US)...II-33
Radiant Research, Inc. (US)...II-33 1
Research Solutions, LLC (US)...II-34 1
6. Global Market Perspective...II-35
Table 10: World Recent Past, Current and Future Analysis for Contract Research Outsourcing by Geographic Region ?US, Europe, Asia and Rest of World Independently Analyzed by Annual Revenues in US$ Million for the Years 2000-2010 (includes corresponding Graph/Chart)...II-35 1
Table 11: World Long-Term Projections for Contract Research Outsourcing by Geographic Region ?US, Europe, Asia and Rest of World Independently Analyzed by Annual Revenues in US$ Million for the Years 2011-2015 (includes corresponding Graph/Chart)...II-36 1
Table 12: World 10-Year Perspective for Contract Research Outsourcing by Geographic Region ? Percentage Breakdown of Revenues for US, Europe, Asia and Rest of World for the Years 2003, 2008 and 2012 (includes corresponding Graph/Chart)...II-37 1
Table 13: World Recent Past, Current and Future Analysis for Contract Research Outsourcing for Drug Discovery by Geographic Region ?US, Europe, Asia and Rest of World Independently Analyzed by Annual Revenues in US$ Million for the Years 2000-2010 (includes corresponding Graph/Chart)...II-38 1
Table 14: World Long-Term Projections for Contract Research Outsourcing for Drug Discovery by Geographic Region ?US, Europe, Asia and Rest of World Independently Analyzed by Annual Revenues in US$ Million for the Years 2011-2015 (includes corresponding Graph/Chart)...II-39 1
Table 15: World 10-Year Perspective for Contract Research Outsourcing for Drug Discovery by Geographic Region ?Percentage Breakdown of Revenues for US, Europe, Asia and Rest of World for the Years 2003, 2008 and 2012 (includes corresponding Graph/Chart)...II-40 1
Table 16: World Recent Past, Current and Future Analysis for Contract Research Outsourcing for Clinical Research by Geographic Region ?US, Europe, Asia and Rest of World Independently Analyzed by Annual Revenues in US$ Million for the Years 2000-2010 (includes corresponding Graph/Chart)...II-41 1
Table 17: World Long-Term Projections for Contract Research Outsourcing for Clinical Research by Geographic Region ?US, Europe, Asia and Rest of World Independently Analyzed by Annual Revenues in US$ Million for the Years 2011-2015 (includes corresponding Graph/Chart)...II-42 1
Table 18: World 10-Year Perspective for Contract Research Outsourcing for Clinical Research by Geographic Region ?Percentage Breakdown of Revenues for US, Europe, Asia-Pacific and Rest of World for the Years 2003, 2008 and 2012 (includes corresponding Graph/Chart)...II-43 1
III. MARKET 38
1. The United States...III-1 13
A. Market Analysis...III-1
Largest Market Worldwide...III-1
Competitive Scenario...III-1
Table 19: US CRO Market (2007): Percentage Breakdown of CRO Revenues by Player Category (includes corresponding Graph/Chart)...III-1
Recent Industry Activity...III-1 3
Focus on Key Players...III-4 1
Contract Research Organizations...III-5 3
Preclinical Laboratories...III-8 3
Site Management Operations...III-11 1
B. Market Analytics...III-12
Table 20: US Recent Past, Current and Future Analysis for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2000- 2010 (includes corresponding Graph/Chart)...III-12 1
Table 21: US Long-Term Projections for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2011-2015 (includes corresponding Graph/Chart)...III-13
Table 22: US 10-Year Perspective for Contract Research Outsourcing by Service Segment ?Percentage Breakdown of Revenues for Drug Discovery and Clinical Research for the Years 2003, 2008 and 2012...III-13 1
2. Europe...III-14 6
A. Market Analysis...III-14
Significant Market in Contract Research Outsourcing...III-14
Market Overview...III-14
Competitive Scenario...III-14
Eastern Europe - Center for Clinical Trials...III-14 1
Recent Industry Activity...III-15 2
Select Players...III-17
ClinTec International Ltd. ?A British CRO...III-17
ICON PLC ?An Irish CRO...III-17
Huntingdon Life Sciences Research, Inc.- A UK-based Preclinical
Laboratory...III-17 1
B. Market Analytics...III-18
Table 23: European Recent Past, Current and Future Analysis for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2000-2010 (includes corresponding Graph/Chart)...III-18 1
Table 24: European Long-Term Projections for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2011-2015 (includes corresponding Graph/Chart)...III-19
Table 25: European 10-Year Perspective for Contract Research Outsourcing by Service Segment ?Percentage Breakdown of Revenues for Drug Discovery and Clinical Research for the Years 2003, 2008 and 2012...III-19 1
3. Asia...III-20 15 0
A. Market Analysis...III-20
Promising Market...III-20
Table 26: CRO Market Size (US$ million) for Clinical Research in Asia (2004 - 08) (includes corresponding Graph/Chart)...III-20
Outsourcing Destinations: China and India...III-20 1
Promoting Role of the Government...III-21
Focus on Key Markets...III-21
India...III-21
A Thriving Clinical Trial Market...III-21 1
Table 27: Indian CRO Market Revenues in US$ Million (2003-2010) (includes corresponding Graph/Chart)...III-22
Reasons for Outsourcing to India...III-22 1
Table 28: Cost of Conducting Clinical Trials: India Vs US (In US$ Million) (includes corresponding Graph/Chart)...III-23
List of Pharmaceutical Companies Outsourcing Clinical Research to India...III-23
SWOT Analysis III-...III-23 1
Competitive Scenario...III-24
Regulatory Environment...III-24 1
Major Contract Research Organizations...III-25
Ace Biomed Pvt. Ltd....III-25
Asian Clinical Trials Limited...III-25
Catalyst Clinical Services Pvt. Ltd....III-25
Clinigene International Limited...III-25
ClinInvent Research Pvt. Ltd....III-25 1
Clintrac International Pvt. Ltd....III-26
Clinsys Clinical Research, Inc....III-26
Lotus Labs Pvt. Ltd....III-26
Nicholas Piramal India Limited....III-26 1
Shasun Chemicals & Drugs Limited...III-27
SIRO Clinpharm Pvt. Ltd....III-27
Vimta Labs...III-27
China...III-27
Factors Favoring Outsourcing to China...III-27 1
SWOT Analysis ...III-28
Policies Governing Clinical Trials in China...III-28 1
Clinical Research Market Size...III-29
Table 29: CRO Market Size (US$ million) for Clinical Research in China (2004 - 08) (includes corresponding Graph/Chart)...III-29
Select Contract Research Organizations...III-29
Astrom Research International...III-29
Atuka Ltd....III-29
Excel PharmaStudies Inc....III-29 1
Gleneagles Clinical Research Center (Singapore)...III-30
Japan...III-30
Table 30: Japanese CRO Market (2007): Percentage Breakdown of Value Sales by Segment- Clinical, Devices, Food & Supplement, SMO/CRC, Pre-Clinical and Others (includes corresponding Graph/Chart)...III-30 1
Recent Industry Activity...III-31 2
B. Market Analytics...III-33
Table 31: Asian Recent Past, Current and Future Analysis for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2000-2010 (includes corresponding Graph/Chart)...III-33 1
Table 32: Asian Long-Term Projections for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2011-2015 (includes corresponding Graph/Chart)...III-34
Table 33: Asian 10-Year Perspective for Contract Research Outsourcing by Service Segment ?Percentage Breakdown of Revenues for Drug Discovery and Clinical Research for the Years 2003, 2008 and 2012...III-34 1
4. Rest of World...III-35 4
A. Market Analysis...III-35
Recent Industry Activity...III-35 2
B. Market Analytics...III-37
Table 34: Rest of World Recent Past, Current and Future Analysis for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2000-2010 (includes corresponding Graph/Chart)...III-37 1
Table 35: Rest of World Long-Term Projections for Contract Research Outsourcing by Service Segment ?Drug Discovery and Clinical Research Independently Analyzed by Annual Revenues in US$ Million for the Years 2011-2015 (includes corresponding Graph/Chart)...III-38
Table 36: Rest of World 10-Year Perspective for Contract Research Outsourcing by Service Segment ?Percentage Breakdown of Revenues for Drug Discovery and Clinical Research for the Years 2003, 2008 and 2012...III-38 1
IV. COMPETITIVE LANDSCAPE 356
Total Companies Profiled: 219 (including Divisions/Subsidiaries - 236 )
--------------------------------------------------------------------------------Region/Country Players
--------------------------------------------------------------------------------
The United States 82
Canada 10
Japan 1
Europe 72
France 6
Germany 11
The United Kingdom 8
Spain 1
Rest of Europe 46
Asia-Pacific (Excluding Japan) 64
Latin America 7