发布时间：2008.3
摘要
This report analyzes the worldwide markets for Biocompatible Materials in Millions of US$. The specific product segments analyzed are Polymeric Materials, Metallic Materials, Natural Materials, and Other Materials. The report provides separate comprehensive analytics for the North America, Japan, Europe, and Rest of World. Annual forecasts are provided for each region and product segment for the period of 2000 through 2015. The report profiles 70 companies including many key and niche players worldwide such as A.P. Pharma, Inc., AST Products, Inc., Angiotech Pharmaceuticals Inc., Artimplant, AST Products, Inc., Biocoat, Inc., BIOSYNTECH, DENTSPLY International Inc., Invibio, Integra LifeSciences Holdings Corporation, Orthovita, SaluMedica, LLC, SurModics, Synthes Inc, and United States Surgical. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
目录及图表
TABLE OF CONTENTS
BIOCOMPATIBLE MATERIALS (Complete Report) Pages : 395 | $3950
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 3 $100
Study Reliability and Reporting Limitations.....I-1
Disclaimers.....I-2
Data Interpretation & Reporting Level.....I-2
Quantitative Techniques & Analytics.....I-2
Product Definition and Scope of Study.....I-3
Polymeric Materials.....I-3
Metallic Materials.....I-3
Natural Materials.....I-3
Other Materials.....I-3
II. EXECUTIVE SUMMARY 51 $2250
1. Industry Overview.....II-1 2 $200
R&D Creating Brighter Avenues.....II-1
Current and Future Analysis.....II-1
Regional Perspective.....II-1
Segment Wise Perspective.....II-1
Factors Determining Market Growth.....II-1
Awareness of Basic Mechanisms of Cell-Material Interaction.....II-1 1 $100
Birth of Cross-Disciplinary Field of Tissue Engineering.....II-2
Rise in Biomaterial Prices.....II-2
Stem-Cell Technology ?A Threat.....II-2 1 $100
2. Product Overview.....II-3 7 $700
Biocompatible Materials ?An Introduction.....II-3
Definition of Biocompatible Materials.....II-3
Applications.....II-3
Orthopedic Applications.....II-3
Cardiovascular Applications.....II-3 1 $100
Dental Applications.....II-4
Biomaterials as Skin Replacements.....II-4
Biomaterials as Scaffolds for Tissue Engineering.....II-4
Product Segments.....II-4
Polymeric Materials.....II-4 1 $100
Hydrogels.....II-5
Biodegradable Polymers.....II-5
Metallic Materials.....II-5 2 $200
Natural Materials.....II-7
Collagen.....II-7
Hyaluronic Acid.....II-7
Other Materials.....II-7
Ceramics.....II-7 1 $100
Bioactive Ceramics.....II-8
Applications.....II-8
Bone Substitutes.....II-8
Articulating Surfaces in Joint Implants.....II-8
Composites.....II-8
Pyloritic Carbon.....II-8 1 $100
Biomaterial Segments and Applications: An Outline.....II-9 1 $100
3. Product Trends.....II-10 3 $300
Biomaterials Play Crucial Role in Implants Market.....II-10
Natural Substances find Increasing Application in Biomaterial Syntheses.....II-10
Plastic Companies Join the Fray as Manufacturers of Biodegradable Materials.....II-10 1 $100
Ceramic Fillings as Substitute for Silver-Tin-Mercury Amalgam Fillings.....II-11
Ceramics Offer Significant Potential in Crown Syntheses.....II-11
Hafnium ?A Promising Material for Biocompatible Coatings.....II-11
Chitin as a New Biomaterial.....II-11
Bioglass - A Potential Material for Bone Regeneration.....II-11 1 $100
Collagen ?An Efficient Biomaterial for Synthetic Vascular Grafts.....II-12
Biopolymers as Biomaterials.....II-12
Bioabsorbable Intelligent Materials.....II-12
Biocompatible Coatings ?A Boon for Medical Implant Applications.....II-12
Nanotechnology ?Revolutionizes Development of Biomaterial Implants.....II-12 1 $100
4. End-Use Market Analysis.....II-13 7 $700
Biosensors.....II-13
Implants .....II-13
Common Orthopedic Implants: Merits and Demerits.....II-13 1 $100
Biocompatibility of Material Implants with Blood.....II-14
Integrating Heparin to Polymeric Surface.....II-14 1 $100
Dental Implants.....II-15
Crown and Bridge Consumption.....II-15
Table 1: Worldwide Dental Implant Market (2005): Percentage Share Breakdown for Nobel Biocare, Straumann, Biomet/3i, Zimmer Dental, Dentsply/ Friadent and Others (includes corresponding Graph/Chart).....II-15
Joint Implant.....II-15
Artificial Organs.....II-15
Artificial Heart.....II-15
Totally Implantable Artificial Heart (TAH) System.....II-15
Pneumatic Total Artificial Heart (PTAH).....II-15 1 $300
Cardiopulmonary Bypass System for Long-term Use.....II-16
Ventricular Assist Device.....II-16
Artificial Blood Vessels.....II-16
Artificial Blood.....II-16
Artificial Skin.....II-16 1 $100
Surface Coatings.....II-17
Materials for Drug Delivery Systems.....II-17
Polyethylene Glycol as a Drug Delivery System.....II-17
Hydrogels as Drug Delivery System.....II-17
Vinylic based Drug Delivery Systems.....II-17
Collagen Based Drug Delivery System.....II-17 1 $100
Electrodes.....II-18
Tissue Replacement Materials.....II-18
Dialysis/Separation/Filtration Systems.....II-18
Dialysis.....II-18 1 $100
Filtration and Separation.....II-19
Cosmetic and Dental Materials.....II-19
Biomaterials for Cosmetic Formulations.....II-19 1 $100
5. Research and Development.....II-20 3 $300
Biocompatible Materials ?Key Research Objectives.....II-20 1 $100
R&D Activity.....II-21
French Inventors Develop Three-Dimensional Filet Stitch Fabric Wall
Reinforcement.....II-21
California Inventor Develops Biocompatible Material.....II-21
Scientists Develop Process for Producing Biocompatible Fibers.....II-21
Penn State Researchers Develop New Niobium Molding Process.....II-21
Doxa Commences Clinical Trials for Novel Biomaterial.....II-21
FzioMed Concludes Preliminary Study for Oxiplex Gel.....II-21 1 $100
MIV抯 Biomaterial Stent Coating Clears Pyrogen Clinical Testing.....II-22 1 $100
6. Regulatory Environment.....II-23 2 $200
FDA Regulations.....II-23
American Society for Testing and Materials (ASTM).....II-23
Joint Research Center (JRC).....II-23
Biocompatibility Testing of Materials.....II-23
Testing Levels.....II-23
General Biocompatibility Testing.....II-23 1 $100
Individual Biocompatibility Testing.....II-24
Testing Methods.....II-24 1 $100
7. Product Introductions/Innovations.....II-25 2 $200
Invibio?Launches ENDOLIGN?Polymer Composite.....II-25
Zimmer Dental Launches the Puros?Dermis Allograft Tissue Matrix.....II-25
Integra Launches Nerve Injury Products.....II-25 1 $100
DePuy Mitek Expands Orthopedics Product Portfolio.....II-26
DSM Dyneema Introduces Polyethylene Fiber.....II-26 1 $100
8. Recent Industry Activity.....II-27 5 $500
Tyco International Acquires Confluent Surgical.....II-27
SurModics Acquires Intralytix抯 Biodegradable Polymer Technology.....II-27
Orthovita Signs a Collaboration Agreement with Aastrom Biosciences for Orthopedic
Products.....II-27
Kuhnil Pharma Acquires Rights from BioSyntech.....II-27
SurModics Licenses Hydrophilic Coating to Devax.....II-27 1 $100
BioSyntech Receives Notice of Allowance from the US Patent and Trademark Office for
BST-CarGel?....II-28
Artimplant Signs License and Development Agreements with Small Bone
Innovations.....II-28
SaluMedica Licenses Proprietary Biomaterial to Spine Medica.....II-28
SurModics Licenses Hydrophilic Technology to Medtronic.....II-28
SurModics Obtains Exclusive Rights from Rutgers University to Biodegradable Polymers
for Ophthalmology.....II-28 1 $100
MIV Therapeutics Inks Research Agreement with University of British Columbia.....II-29
Zimmer Acquires Implex.....II-29
Biomet Acquires Interpore.....II-29
Angiotech Acquires NeuColl.....II-29
Synthes-Stratec Inc. and Mathys Medizinaltechnik AG Merge.....II-29 1 $100
Kyocera and Kobe Steel Forms a Joint Venture.....II-30
Angiotech Expands Biomaterial Licensing Agreement with Poly-Med.....II-30
Genzyme Corp Enters into Agreement with Wyeth Pharmaceuticals.....II-30
OctoPlus Grants License to SurModics to Acquire Two Novel Biodegradable
Polymers.....II-30 1 $100
GP Surgical Receives FDA Approval for TiMESH.....II-31 1 $100
9. Focus on Select Players.....II-32 5 $500
A.P. Pharma, Inc. (USA).....II-32
Angiotech Pharmaceuticals Inc. (Canada).....II-32
Artimplant (Sweden).....II-32 1 $100
AST Products, Inc. (USA).....II-33
Biocoat, Inc. (USA).....II-33
BIOSYNTECH (Canada).....II-33
DENTSPLY International Inc. (USA).....II-33 1 $100
Invibio (UK).....II-34
Integra LifeSciences Holdings Corporation (USA).....II-34 1 $100
Orthovita (USA).....II-35
SaluMedica, LLC (USA).....II-35
SurModics (USA).....II-35 1 $100
Synthes Inc (USA).....II-36
United States Surgical (USA).....II-36 1 $100
10. Global Market Perspective.....II-37
Table 2: World Recent Past, Current and Future Analysis for Biocompatible Materials by Geographic Region ?North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-37 1 $300
Table 3: World Long-term Projections for Biocompatible Materials by Geographic Region 朜orth America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-38 1 $300
Table 4: World 10-Year Perspective for Biocompatible Materials by Geographic Region ?Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2003, 2008 and 2012 (includes corresponding Graph/Chart).....II-39 1 $300
Table 5: World Recent Past, Current and Future Analysis for Polymeric Materials by Geographic Region ?North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-40 1 $300
Table 6: World Long-term Projections for Polymeric Materials by Geographic Region 朜orth America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-41 1 $300
Table 7: World 10-Year Perspective for Polymeric Materials by Geographic Region ?Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2003, 2008 and 2012 (includes corresponding Graph/Chart).....II-42 1 $300
Table 8: World Recent Past, Current and Future Analysis for Metallic Materials by Geographic Region ?North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-43 1 $300
Table 9: World Long-term Projections for Metallic Materials by Geographic Region 朜orth America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-44 1 $300
Table 10: World 10-Year Perspective for Metallic Materials by Geographic Region ?Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2003, 2008 and 2012 (includes corresponding Graph/Chart).....II-45 1 $300
Table 11: World Recent Past, Current and Future Analysis for Natural Materials by Geographic Region ?North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-46 1 $300
Table 12: World Long-term Projections for Natural Materials by Geographic Region 朜orth America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-47 1 $300
Table 13: World 10-Year Perspective for Natural Materials by Geographic Region ?Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2003, 2008 and 2012 (includes corresponding Graph/Chart).....II-48 1 $300
Table 14: World Recent Past, Current and Future Analysis for Other Materials by Geographic Region ?North America, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-49 1 $300
Table 15: World Long-term Projections for Other Materials by Geographic Region 朜orth America, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-50 1 $300
Table 16: World 10-Year Perspective for Other Materials by Geographic Region ?Percentage Breakdown of Dollar Sales for North America, Japan, Europe, and Rest of World Markets for Years 2003, 2008 and 2012(includes corresponding Graph/Chart).....II-51 1 $300
III. MARKET 25 $1950
1. North America.....III-1 13 $975
A. Market Analysis.....III-1
Outlook.....III-1
Regulatory Environment.....III-1
FDA Regulations.....III-1 1 $75
American Society for Testing and Materials (ASTM).....III-2
R&D Activity.....III-2 1 $75
Potential Biomaterial Shortage.....III-3
Effects of Potential Shortages.....III-3 1 $75
Product Introductions/ Innovations.....III-4
Strategic Corporate Developments.....III-4 4 $300
Select Players.....III-8 4 $300
B. Market Analytics.....III-12
Table 17: North America Recent Past, Current and Future Analysis for Biocompatible Materials by Product Segment ?Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-12 1 $150
Table 18: North America Long-term Projections for Biocompatible Materials by Product Segment - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-13
Table 19: North America 10-Year Perspective for Biocompatible Materials by Product Segment ?Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for 2003, 2008 and 2012 (includes corresponding Graph/Chart).....III-13 1 $150
2. Japan.....III-14 5 $425
A. Market Analysis.....III-14
Outlook.....III-14
An Overview.....III-14
Import Scenario: Implants.....III-14 1 $75
Table 20: Japanese Percentage Imports by Implant Type (includes corresponding Graph/Chart).....III-15
History.....III-15
Major Biomaterial Research Groups.....III-15
Institute of Biomedical Engineering (Tokyo Women抯 Medical University).....III-15
Tissue Engineering Research Institute (Kyoto University).....III-15
Institute of Biomaterials and Bioengineering (Tokyo Medical and Dental
University).....III-15 1 $150
Principal Research Institutions.....III-16
Regulatory Environment.....III-16
Medical Affairs Law.....III-16
Strategic Corporate Development.....III-16 1 $75
B. Market Analytics.....III-17
Table 21: Japanese Recent Past, Current and Future Analysis for Biocompatible Materials by Product Segment ?Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-17 1 $150
Table 22: Japanese Long-term Projections for Biocompatible Materials by Product Segment - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-18
Table 23: Japanese 10-Year Perspective for Biocompatible Materials by Product Segment ?Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for 2003, 2008 and 2012 (includes corresponding Graph/Chart).....III-18 1 $150
3. Europe.....III-19 5 $375
A. Market Analysis.....III-19
Outlook.....III-19
UK Bioceramic Market.....III-19
Regulatory Environment.....III-19
Government Regulations.....III-19
Joint Research Center (JRC).....III-19 1 $75
Product Introductions/Innovations.....III-20
Strategic Corporate Developments.....III-20 1 $75
Review of Select Players.....III-21 1 $75
B. Market Analytics.....III-22
Table 24: European Recent Past, Current and Future Analysis for Biocompatible Materials by Product Segment ?Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-22 1 $150
Table 25: European Long-term Projections for Biocompatible Materials by Product Segment - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-23
Table 26: European 10-Year Perspective for Biocompatible Materials by Product Segment ?Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for Years 2003, 2008 and 2012 (includes corresponding Graph/Chart).....III-23 1 $150
4. Rest of World.....III-24 2 $300
A. Market Analysis.....III-24
Outlook.....III-24
Strategic Corporate Development.....III-24
B. Market Analytics.....III-24
Table 27: Rest of World Recent Past, Current and Future Analysis for Biocompatible Materials by Product Segment ?Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-24 1 $150
Table 28: Rest of World Long-term Projections for Biocompatible Materials by Product Segment - Polymeric Materials, Metallic Materials, Natural Materials & Other Materials Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-25
Table 29: Rest of World 10-Year Perspective for Biocompatible Materials by Product Segment ?Percentage Breakdown of Dollar Sales for Polymeric Materials, Metallic Materials, Natural Materials and Other Materials Markets for 2003, 2008 and 2012 (includes corresponding Graph/Chart).....III-25 1 $150
IV. COMPETITIVE LANDSCAPE 302 $995
Total Companies Profiled: 70 (including Divisions/Subsidiaries - 80)
--------------------------------------------------------------------------------Region/Country Players
--------------------------------------------------------------------------------
The United States 53
Canada 4
Japan 2
Europe 20
France 1
Germany 3
The United Kingdom 4
Rest of Europe 12
Middle East 1