发布时间：2008.4
摘要
This report analyzes the worldwide markets for Chiral Technology in US$ Million. Chiral Technology Enabling Products analyzed are Intermediates, Analytical, and Others. The specific end-use segments discussed are Pharmaceuticals, and Agrochemicals. The report provides separate comprehensive analytics for the US, Japan, Europe, and Rest of World. Annual forecasts are provided for each region for the period of 2000 through 2015. The report profiles 40 companies including many key and niche players worldwide such as Albemarle Corporation, BASF AG, Cambrex Corp., Chiral Quest Inc., Dalco ChromTech AB, Daicel Chemical Industries Ltd., DSM Pharmaceutical Products, DowpharmaSM, Johnson Matthey PLC, Regis Technologies Inc., Shasun Chemicals and Drugs Limited, Solvias, Sigma Aldrich Corp, and Suven Life Sciences Ltd. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
目录及图表
TABLE OF CONTENTS
CHIRAL TECHNOLOGY (Complete Report) Pages : 286 | $3950
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 4 $100
Study Reliability and Reporting Limitations.....I-1
Disclaimers.....I-2
Data Interpretation & Reporting Level.....I-2
Quantitative Techniques & Analytics.....I-3
Product Definitions and Scope of Study.....I-3
Chiral Technology Enabling Products.....I-4
Chiral Intermediates.....I-4
Analytical Products.....I-4
Other Products.....I-4
Chiral Technology End-Use Products.....I-4
Pharmaceuticals.....I-4
Agrochemicals.....I-4
II. EXECUTIVE SUMMARY 62 $2250
1. Introduction.....II-1 3 $600
An Insight into Chiral Technology.....II-1
Techniques Used for Achieving Single-Isomers.....II-1 1 $100
Table 1: World Chiral Technology Market (2002 & 2010): Percentage Breakdown of Revenues by Techniques- Traditional Methods, Asymmetric Methods, and Biological Methods (includes corresponding Graph/Chart).....II-2
Importance and Advancements.....II-2 2 $600
2. Global Market Overview.....II-4 3 $300
Outlook and Trends.....II-4
Good Tidings for Chiral Technology.....II-4 1 $100
Market Drivers.....II-5
Demand for Chiral-based Therapeutic Drugs Augments Growth.....II-5
New Legislations Push Chiral Technology Demand.....II-5 1 $100
Key Trends.....II-6
Organizations Extend Approaches.....II-6
Companies?Association with Universities.....II-6 1 $100
3. Chiral Technology ?An Overview.....II-7 9 $700
Definitions.....II-7
Chiral Technology Enabling Products.....II-7
Chiral Intermediates.....II-7
Analytical Products.....II-7
Other Products.....II-7
Chiral Technology End-Use Markets.....II-7
Pharmaceuticals.....II-7 1 $100
Agrochemicals.....II-8
Description.....II-8 1 $100
Functioning of Chiral Molecules.....II-9
Chiral Preparation Process.....II-9
Traditional Methods.....II-9
Biological Methods.....II-9 1 $100
Asymmetric Methods.....II-10
Chiral Separation.....II-10
Chromatography ?The Widely Used Method for Separation.....II-10 1 $100
How it Works?.....II-11
Chiral Mobile Phase Additive (CMPA).....II-11
Chiral Stationary Phase (CSP).....II-11 1 $100
Chiral Recognition.....II-12
Protein Chiral Stationary Phases.....II-12
Carbohydrate Columns.....II-12
Pirkle Columns.....II-12
Crystallization.....II-12 1 $100
Solvent Extraction.....II-13
Kinetic Resolution.....II-13 1 $100
Capillary Electrophoresis.....II-14
Receptor Based Resolution.....II-14
Miscellaneous Separative Techniques.....II-14
Chiral Synthesis.....II-14 2 $200
4. Chiral Technology ?Development vs. Acquisition.....II-16 2 $200
In-House Creation & Development.....II-16
Acquisition of Technology.....II-16 1 $100
揈conomics?of Chiral Technology.....II-17 1 $100
5. Chiral Analysis Products.....II-18 4 $400
Chiral Analytical Chromatography.....II-18
Chiral Liquid Chromatography.....II-18
Supercritical Fluid Chromatography - Substitute to LC for Enantiomer
Separations.....II-18
Chiral Gas Chromatography.....II-18 1 $100
Chiral Simulated Moving Bed Chromatography.....II-19
Partition Chromatography.....II-19
Adsorption Chromatography.....II-19
Computer Assisted Resolution.....II-19 1 $100
Chiral Polarimetry.....II-20
Other Chiral Analytical Techniques.....II-20
Calorimetry.....II-20
Differential Scanning Calorimetry (DSC).....II-20
Enzymatic Assay.....II-20 1 $100
Immunoassay.....II-21
Isotope Dilution.....II-21
Nuclear Magnetic Resonance (NMR).....II-21
X-Ray Crystallography.....II-21 1 $100
6. Application Markets.....II-22 10 $800
Pharmaceuticals ?The Largest Market.....II-22
Changing Face of the Pharmaceutical Industry.....II-22
Analysis of Chiral Drugs.....II-22 1 $100
Select Companies Involved in Chiral Technology Market.....II-23
Table 2: Single-Enantiomer Drugs Market Worldwide (2006): Sales of Select Leading Brands (In US$ Billion) (includes corresponding Graph/Chart).....II-23 1 $300
Drugs Built on Chiral Technology.....II-24
Analgesics.....II-24
Anesthetics.....II-24
Anti-Infective Products.....II-24 1 $100
Cardiovascular System (CVS) Products.....II-25
Angiotensin-Converting Enzyme (ACE) Inhibitors.....II-25
Beta-Blockers.....II-25
Calcium Channel Blockers.....II-25
Diuretics.....II-25
Vasodilators.....II-25
Central Nervous System (CNS) Agents.....II-25
Anticonvulsants.....II-25 1 $100
Sedatives and Tranquilizers.....II-26
Stimulants and Antidepressants.....II-26
Oncogenic (Cancer-Treatment) Products.....II-26
Biochemicals.....II-26
Oligonucleotides.....II-26 1 $100
Oxyacids.....II-27
Amino Acids.....II-27
Sugars and Other Oligosaccharides.....II-27 1 $100
Vitamins.....II-28
Peptides.....II-28 1 $100
Pesticides ?A Thriving Market.....II-29
Herbicides.....II-29
Insecticides.....II-29 1 $100
Fungicides.....II-30
Other Products.....II-30
Liquid Crystals.....II-30 1 $100
Flavor and Aroma Chemicals.....II-31 1 $100
7. Chiral Isomerism.....II-32 2 $200
Organic Chemical Isomerism Types.....II-32
Structural Isomerism.....II-32
Chain Isomerism.....II-32
Position Isomerism.....II-32
Functional Group Isomerism.....II-32
Stereoisomerism.....II-32 1 $100
Dynamic Isomerism (Tautomerism).....II-33
Patents.....II-33 1 $100
8. Regulatory & Environmental Issues.....II-34 1 $100
Regulatory & Environmental Issues.....II-34 1 $100
9. Product Introductions.....II-35 2 $200
Degussa Develops Novel Processes to Synthesize (S) CAP.....II-35
Regis Technologies, Inc. Launches RegisPack Chiral.....II-35
Columns.....II-35
Sigma-Aldrich Introduces ChiroSolv?Kits.....II-35
Sigma-Aldrich Launches Ascentis Express HPLC Columns.....II-35 1 $100
Evolved Nanomaterial Releases Revolutionary Analytical Chiral Column.....II-36
BASF Develops Novel Process to Produce Chiral Intermediates.....II-36
Chiral Quest Launches C3 TunePhos.....II-36 1 $100
10. Recent Industry Activity.....II-37 3 $300
Cambrex to Buy ProSyntest AS.....II-37
Johnson Matthey and X-Zyme Sign Licensing Agreement.....II-37
Chiral Quest Starts a New Production Facility.....II-37
Chiral Quest Completes Reverse Merger with Surg II.....II-37
DSM and IEP Extend Partnership.....II-37 1 $100
Shasun Chemicals Acquires Rhodia Pharma Solutions.....II-38
Sigma-Aldrich Corp Acquires Astec.....II-38
Solvias Receives License for MeOBIPHEP Catalyst Technology.....II-38
Codexis Acquires Juelich Fine Chemicals.....II-38
ChiroBlock Exits from Chiral Compounds Business.....II-38
Chiral Quest Opens New Facility in China.....II-38
Chiral Quest to Supply C3 TunePhos to Phoenix Chemicals.....II-38 1 $100
Lonza and Codexis Sign Agreement for Biocatalysis Process.....II-39
DSM Signs Licensing Agreement with Chiral Quest.....II-39
Chiral Quest Signs Distribution Agreement with Aldrich Chemical.....II-39
BASF and Solvias to Collaborate on Chiral Molecule Development.....II-39
Chiral Quest and Avantium Enter into Partnership.....II-39 1 $100
11. Focus on Select Players.....II-40 5 $500
Albemarle Corporation (USA).....II-40
BASF AG (Germany).....II-40
Cambrex Corp. (USA).....II-40 1 $100
Chiral Quest Inc (US).....II-41
Dalco ChromTech AB (Sweden).....II-41
Daicel Chemical Industries Ltd. (Japan).....II-41
DSM Pharmaceutical Products (Netherlands).....II-41 1 $100
DowpharmaSM (USA).....II-42
Johnson Matthey PLC (UK).....II-42
Regis Technologies Inc (USA).....II-42 1 $100
Shasun Chemicals and Drugs Limited (India).....II-43
Solvias (Switzerland).....II-43
Sigma Aldrich Corp (USA).....II-43
Suven Life Sciences Ltd. (USA).....II-43 2 $200
12. Global Market Perspective.....II-45
Table 3: World Recent Past, Current & Future Analysis for Chiral Technology Enabling Products by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-45 1 $300
Table 4: World Long-term Projections for Chiral Technology Enabling Products by Geographic Region ? US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-46 1 $300
Table 5: World 10-Year Perspective for Chiral Technology Enabling Products by Geographic Region ?Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....II-47 1 $300
Table 6: World Recent Past, Current & Future Analysis for Chiral Intermediates by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-48 1 $300
Table 7: World Long-term Projections for Chiral Intermediates by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-49 1 $300
Table 8: World 10-Year Perspective for Chiral Intermediates by Geographic Region ?Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....II-50 1 $300
Table 9: World Recent Past, Current & Future Analysis for Chiral Analytical Products by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-51 1 $300
Table 10: World Long-term Projections for Chiral Analytical Products by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-52 1 $300
Table 11: World 10-Year Perspective for Chiral Analytical Products by Geographic Region ?Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....II-53 1 $300
Table 12: World Recent Past, Current & Future Analysis for Other Chiral Technology Enabling Products by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-54 1 $300
Table 13: World Long-term Projections for Other Chiral Technology Enabling Products by Geographic Region ? US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-55 1 $300
Table 14: World 10-Year Perspective for Other Chiral Technology Enabling Products by Geographic Region ?Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....II-56 1 $300
Table 15: World Recent Past, Current & Future Analysis for Chiral Technology in Pharmaceuticals by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-57 1 $300
Table 16: World Long-term Projections for Chiral Technology in Pharmaceuticals by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-58 1 $300
Table 17: World 10-Year Perspective for Chiral Technology in Pharmaceuticals by Geographic Region ?Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....II-59 1 $300
Table 18: World Recent Past, Current & Future Analysis for Chiral Technology in Agrochemicals by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....II-60 1 $300
Table 19: World Long-term Projections for Chiral Technology in Agrochemicals by Geographic Region ?US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....II-61 1 $300
Table 20: World 10-Year Perspective for Chiral Technology in Agrochemicals by Geographic Region ?Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....II-62 1 $300
III. MARKET 27 $1950
1. The United States.....III-1 9 $775
A. Market Analysis.....III-1
Overview.....III-1
Product Introductions/Developments.....III-1 1 $75
Strategic Corporate Developments.....III-2 1 $75
Select Players.....III-3
Albemarle Corporation.....III-3
Cambrex Corp......III-3 1 $75
Chiral Quest Inc.....III-4
DowpharmaSM.....III-4
Regis Technologies Inc.....III-4 1 $75
Sigma Aldrich Corp.....III-5
Suven Life Sciences Ltd......III-5 1 $75
B. Market Analytics.....III-6
Table 21: US Recent Past, Current & Future Analysis for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-6
Table 22: US Long-term Projections for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-6 1 $150
Table 23: US 10-Year Perspective for Chiral Technology Enabling Products by Product Segment ?Percentage Breakdown of Value Sales for Intermediates, Analytical, and Other Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....III-7 1 $150
Table 24: US Recent Past, Current & Future Analysis for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-8
Table 25: US Long-term Projections for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-8 1 $150
Table 26: US 10-Year Perspective for Chiral Technology by End-Use Segment ?Percentage Breakdown of Value Sales for Pharmaceuticals, and Agrochemicals Markets for Years 2003, 2008 & 2012.....III-9 1 $150
2. Japan.....III-10 5 $475
A. Market Analysis.....III-10
Outlook.....III-10
Daicel Chemical Industries Ltd ?A Major Player.....III-10 1 $75
B. Market Analytics.....III-11
Table 27: Japanese Recent Past, Current & Future Analysis for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-11
Table 28: Japanese Long-term Projections for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-11 1 $150
Table 29: Japanese 10-Year Perspective for Chiral Technology Enabling Products by Product Segment ?Percentage Breakdown of Value Sales for Intermediates, Analytical, and Other Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....III-12 1 $150
Table 30: Japanese Recent Past, Current & Future Analysis for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-13
Table 31: Japanese Long-term Projections for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-13 1 $150
Table 32: Japanese 10-Year Perspective for Chiral Technology by End-Use Segment ?Percentage Breakdown of Value Sales for Pharmaceuticals and Agrochemicals Markets for Years 2003, 2008 & 2012.....III-14 1 $150
3. Europe.....III-15 8 $700
A. Market Analysis.....III-15
Overview.....III-15
Product Introductions.....III-15 1 $75
Strategic Corporate Developments.....III-16 1 $75
Select Players.....III-17
BASF AG (Germany).....III-17 1 $75
Dalco ChromTech AB (Sweden).....III-18
DSM Pharmaceutical Products (Netherlands).....III-18
Johnson Matthey PLC (UK).....III-18 1 $75
Solvias (Switzerland).....III-19
B. Market Analytics.....III-19
Table 33: European Recent Past, Current & Future Analysis for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-19 1 $150
Table 34: European Long-term Projections for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-20
Table 35: European 10-Year Perspective for Chiral Technology Enabling Products by Product Segment ?Percentage Breakdown of Value Sales for Intermediates, Analytical, and Other Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....III-20 1 $150
Table 36: European Recent Past, Current & Future Analysis for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-21
Table 37: European Long-term Projections for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-21 1 $150
Table 38: European 10-Year Perspective for Chiral Technology by End-Use Segment ?Percentage Breakdown of Value Sales for Pharmaceuticals, and Agrochemicals Markets for Years 2003, 2008 & 2012.....III-22 1 $150
4. Rest of World.....III-23 5 $675
A. Market Analysis.....III-23
Outlook.....III-23
India.....III-23
Chiral Drugs in Indian Market.....III-23
China-A Hub for Pharmaceutical Manufacturing.....III-23
Strategic Corporate Development.....III-23
Shasun Chemicals and Drugs Limited ?A Major Indian Player.....III-23 1 $75
B. Market Analytics.....III-24
Table 39: Rest of World Recent Past, Current & Future Analysis for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-24 1 $150
Table 40: Rest of World Long-term Projections for Chiral Technology Enabling Products by Product Segment ?Intermediates, Analytical, and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-25
Table 41: Rest of World 10-Year Perspective for Chiral Technology Enabling Products by Product Segment ?Percentage Breakdown of Value Sales for Intermediates, Analytical, and Other Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart).....III-25 1 $150
Table 42: Rest of World Recent Past, Current & Future Analysis for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart).....III-26
Table 43: Rest of World Long-term Projections for Chiral Technology by End-Use Segment ?Pharmaceuticals, and Agrochemicals Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart).....III-26 1 $150
Table 44: Rest of World 10-Year Perspective for Chiral Technology by End-Use Segment ?Percentage Breakdown of Value Sales for Pharmaceuticals, and Agrochemicals Markets for Years 2003, 2008 & 2012.....III-27 1 $150
IV. COMPETITIVE LANDSCAPE 185 $995
Total Companies Profiled: 40 (including Divisions/Subsidiaries
- 50)
--------------------------------------------------------------------------------Region/Country Players
--------------------------------------------------------------------------------
The United States 31
Canada 1
Japan 2
Europe 14
France 4
Germany 2
The United Kingdom 3
Italy 1
Rest of Europe 4
Asia-Pacific (Excluding Japan) 2