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心脏标记诊断测试市场研究报告——Cardiac Marker Diagnostic Testing Markets
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纸介版价格:美元/篇 字数:万字
电子版价格:3400美元/篇 页数:
纸介版+电子版价格:美元 图表数:
完成日期:2008-05-16
关键字: 心脏标记|Cardiac Marker
 联系方式: 北京:010-51266615 010-82863480/1/2/5 传真:010-82863486  上海:021-64871266 021-64872612 传真:021-64872324    [在线订购]  

发布时间:2008年5月1日

摘要:

The purpose of this TriMark Publications report is to describe the specific market segment of the in vitro diagnostics (IVD) market devoted to cardiac marker testing. This study examines clinical measurement devices and their reagents and supplies as used in hospitals, clinics and doctor's offices. This examination is arranged to provide the reader with an overview of the outstanding diagnostic test market segments of cardiac care, with evidence that these segments are poised for high future growth. An overview of the diagnostic testing cardiac marker market is presented with the latest information regarding emerging new products and industry trends. It will not only quantify but also qualify the cardiac marker market segments as an area of research, product development and investment. Forecasts of the cardiac marker market and an analysis of products in the worldwide diagnostics market will provide a basis for understanding the significance of past developments and future possibilities within this diagnostic category.



正文目录:

Table of Contents:

  1. 1. Overview 6
  2. 1.1 Statement of Report 6
  3. 1.2 Objectives of This Report 6
  4. 1.3 Scope of This Report 8
  5. 1.4 Methodology 8
  6. 1.5 Executive Summary 8
  7. 2. Introduction 11
  8. 2.1 Global Diagnostic Products Industry 11
  9. 2.2 Barriers to Entry 14
  10. 2.3 Company Evaluation Overview 15
  11. 2.4 Market Outlook 16
  12. 2.5 Technologies and Products that are the Most Successful in the New IVD Environment 16
  13. 3. Cardiac Marker Testing Markets: Market Segment Analysis: Size, Growth and Share 18
  14. 3.1 Global Cardiac Marker Diagnostic Testing Markets 18
  15. 3.1.1 Clinical Utility of Cardiac Markers 22
  16. 3.1.2 Market Drivers in the Cardiac Marker Diagnostics Testing Sector 24
  17. 3.1.3 Market Restraints in Cardiac Marker Testing Segment 24
  18. 3.1.4 Principal Market Segments for Cardiac Marker Testing 24
  19. 3.1.5 Key Players in the Cardiac Marker Diagnostics Testing Segment 25
  20. 3.1.6 Cardiac Marker Testing Sector Analysis 26
  21. 3.1.7 Cardiac Marker Market Share 26
  22. 3.2 U.S. Cardiac Marker Testing Market 26
  23. 3.2.1 Market Overview 26
  24. 3.2.2 Diagnostic Test Categories 27
  25. 3.2.3 U.S. Hospital POC Cardiac Markers 28
  26. 3.3 European Cardiac Marker Diagnostic Test Market 29
  27. 3.3.1 German Diagnostic Markets 32
  28. 3.3.2 U.K. Diagnostic Testing Market 33
  29. 3.3.2.1 U.K. Market Statistics 33
  30. 3.3.2.2 U.K. Competitive Analysis 34
  31. 3.3.2.3 U.K. Market Access 35
  32. 3.3.3 Italy 35
  33. 3.3.4 France 36
  34. 3.3.5 Spain 36
  35. 3.3.6 Belgium 36
  36. 3.3.7 Switzerland 37
  37. 3.3.8 Barriers to Entry to European Market 37
  38. 3.4 Japanese Diagnostic Testing Market 37
  39. 3.5 Chinese Diagnostic Testing Market 37
  40. 3.6 Canadian Diagnostic Market 40
  41. 3.7 Cardiac Marker Testing Individual Markets 40
  42. 3.7.1 Clinical Overview 40
  43. 3.7.2 Cardiac Acute Disease Markers 41
  44. 3.7.3 Market Overview 42
  45. 3.7.3.1 AMI and Troponins 44
  46. 3.7.3.2 Market Size and Growth Projections 47
  47. 3.7.3.3 Clinical Use of Cardiac Troponins 48
  48. 3.7.3.4 TnI and TnT Market Drivers 51
  49. 3.7.3.5 TnI and TnT Market Restraints 51
  50. 3.7.3.6 New Tests for Troponin 52
  51. 3.7.4 CK-MB and Cardiac Enzymes 52
  52. 3.7.4.1 CK Enzymes 52
  53. 3.7.4.2 Market Size and Growth Projections 53
  54. 3.7.4.3 CK-MB: Market Drivers 54
  55. 3.7.4.4 CK-MB: Market Restraints 54
  56. 3.7.5 Myoglobin 54
  57. 3.7.5.1 Market Size and Growth Projections 54
  58. 3.7.5.2 Clinical Use of Myoglobin 55
  59. 3.7.5.3 Myoglobin Market Drivers 56
  60. 3.7.5.4 Myoglobin Market Restraints 56
  61. 3.7.6 BNP 56
  62. 3.7.6.1 Market Overview 56
  63. 3.7.6.2 Market Size and Growth Projections 58
  64. 3.7.6.3 Commercial Assays for BNP and NT-proBNP 58
  65. 3.7.6.4 Competitive Landscape 60
  66. 3.7.6.5 BNP Test Market Share 60
  67. 3.7.6.6 Clinical Applications of BNP 62
  68. 3.7.6.7 BNP Market Drivers 64
  69. 3.7.6.8 BNP Market Restraints 65
  70. 3.7.7 Albumin 65
  71. 3.7.7.1 Intact Albumin 65
  72. 3.7.7.2 Albumin Cobalt Binding Test 65
  73. 3.7.7.3 Ischemic Modified Albumin 66
  74. 3.7.7.4 Microalbuminuria 68
  75. 3.7.8 Key Players in Cardiac Markers 68
  76. 3.7.9 Cardiac Marker Controls 77
  77. 3.7.10 Evaluation of Cardiac Markers 77
  78. 3.7.11 Cardiac Markers Use in Clinical Decisions 78
  79. 3.7.12 Status of Cardiac Markers in the ER 78
  80. 3.7.13 Cardiac Markers in Renal Failure 78
  81. 3.7.14 Troponins in Non-Ischemic Heart Disease 79
  82. 3.7.15 Market Restraints 79
  83. 3.7.16 Market Drivers 80
  84. 3.7.17 Cardiac Panels 80
  85. 3.7.18 POC Cardiac Markers 80
  86. 3.7.18.1 Market Size and Growth Rate 80
  87. 3.7.18.2 Market Restraints 81
  88. 3.7.18.3 The Next Wave 82
  89. 4. Cardiovascular Disease Markers 86
  90. 4.1 Cholesterol, HDL and LDL 86
  91. 4.1.1 Cholesterol Testing Market Forecasts 87
  92. 4.1.2 Cholesterol Market Growth Drivers 87
  93. 4.1.3 Market Outlook: U.S. Market Analysis 87
  94. 4.1.4 Trends and Issues 88
  95. 4.1.5 Key Players in the Cholesterol OTC Kit Market 88
  96. 4.2 Homocysteine 88
  97. 4.3 Fibrinogen 89
  98. 4.4 C-Reactive Protein 89
  99. 4.5 Lipoprotein Fractions 91
  100. 4.6 Pulmonary Embolism (D-Dimer Test) 92
  101. 4.7 Oxidized LDL and HDL 92
  102. 4.8 Stroke 92
  103. 5. Cardiac Marker Testing Development Issues 94
  104. 5.1 Genetic Testing and Personalized Medicine 94
  105. 5.2 Preventive Medicine 94
  106. 5.3 Patient Safety and Quality Measures 94
  107. 5.4 Reimbursement 95
  108. 5.5 Cardiovascular 97
  109. 5.6 Screening for Diabetes 97
  110. 5.7 Other Reimbursement Concerns 98
  111. 5.7.1 Reimbursement for Routine Venipuncture 98
  112. 5.7.2 Japanese Reimbursements for Medical Devices 98
  113. 5.8 CPT Test Codes and Payment Amounts 98
  114. 5.9 Rapid Near-Patient Testing in Hospitals 99
  115. 5.10 Satellite Facilities 99
  116. 5.11 Regionalization of Laboratory Care 100
  117. 5.12 Requirements for POCT 101
  118. 5.12.1 Benefits of POCT 102
  119. 5.12.2 Turnaround Time for POCT 103
  120. 5.13 Clinical Laboratory Improvement Amendments (CLIA) 103
  121. 5.14 Quality Assurance Issues 104
  122. 5.15 Political Control 105
  123. 5.16 Regulatory Requirements 105
  124. 5.17 Recordkeeping and Data Management 105
  125. 5.17.1 Effectiveness of Clinical Outcomes 105
  126. 6. Business Trends in the Industry 106
  127. 6.1 Sector Consolidation 106
  128. 6.2 Diagnostic Testing Growth Trends 106
  129. 6.3 Acquisition, License Agreements, Internal Development and Partnerships 108
  130. 6.4 Product Testing Depth in Cardiac Marker Testing 111
  131. 6.5 Government Regulation 111
  132. 6.5.1 U.S. Regulation 111
  133. 6.5.1.1 Importing Medical Devices into the U.S. 112
  134. 6.5.1.2 Exporting Medical Devices from the U.S. 113
  135. 6.5.2 U.K. Regulations 113
  136. 6.5.3 E.U. Regulations 114
  137. 6.5.4 Japanese Regulations 115
  138. 6.5.5 Chinese Regulations 116
  139. 6.6 Barriers to Growth 117
  140. 6.7 Drivers of Growth 117
  141. 6.8 Product Launches and Developments 117
  142. 7. Important Technology Trends 119
  143. 7.1 Trends in Cardiac Marker Diagnostic Testing 119
  144. 7.1.1 Fatty Acid Binding Protein 120
  145. 7.1.2 Glycogen Phosphorylase Isoenzyme BB 120
  146. 7.1.3 S-100 Protein 120
  147. 7.1.4 Cobalt-Binding Albumin 120
  148. 7.1.5 Myosin Light Chains 121
  149. 7.2 Cardiac Biomarker Research 121
  150. 7.2.1 Myeloperoxidase 121
  151. 7.2.2 Glutathione Peroxidase 122
  152. 7.2.3 Antioxidant Biomarkers 122
  153. 7.2.4 Oxidative Biomarkers 122
  154. 7.2.5 Inflammatory Biomarkers 123
  155. 7.2.6 Nitrosative Biomarkers 123
  156. 7.2.7 Hemostatic Biomarkers 124
  157. 7.3 Potential Stroke Markers 124
  158. 7.3.1 Pharmacogenomics: Cardiovascular Drugs and Proteomic Markers 125
  159. 7.3.2 Cardiac Proteomics 125
  160. 7.3.3 Drivers for Cardiovascular Proteomic Markers 125
  161. 7.3.4 Barriers to Cardiovascular Proteomic Markers 126
  162. 7.4 Future Developments for Cardiovascular Markers 126
  163. 7.5 Research Questions 126
  164. 7.5.1 Roche's Biomarker Strategy 129
  165. 7.5.2 Biomarkers for Unstable Angina 130
  166. 7.6 Lp-PLA2 130
  167. 7.7 Urotensin 131
  168. 8. Company Profiles 132
  169. 8.1 Abbott Laboratories 132
  170. 8.2 Ani Biotech 136
  171. 8.3 Axis-Shield 137
  172. 8.4 Bayer Corporation 138
  173. 8.5 Beckman Coulter 139
  174. 8.6 Biosite, Inc. (now a brand of Inverness Medical Innovations) 141
  175. 8.7 Inverness Medical Innovations 144
  176. 8.8 Johnson & Johnson 146
  177. 8.9 LifeSign 146
  178. 8.10 Olympus America 146
  179. 8.11 PreMD, Inc. 147
  180. 8.12 Randox Laboratories 147
  181. 8.13 Response Biomedical 147
  182. 8.14 Roche Diagnostics 148
  183. 8.16 Sierra Resources International 152
  184. 8.17 Spectral Diagnostics, Inc. 152
  185. LIST OF FIGURES
  186. Figure 2.1: Lab Industry Market Share 13
  187. Figure 2.2: Market Share of Major Lab Testing Segments 14
  188. 图表目录:
  189. LIST OF TABLES
  190. Table 2.1: World Population and Growth, 2000-2024 11
  191. Table 2.2: Worldwide Market Share IVD Companies 12
  192. Table 2.3: U.S. In Vitro Central Lab Diagnostic Testing, 2001-2007 13
  193. Table 2.4: Worldwide Near-Patient Diagnostic Testing, 2001-2007 13
  194. Table 3.1: Cardiac Marker Markets by Country, 2002-2010 18
  195. Table 3.2: Total Global Cardiac Marker Market, 2002-2010 18
  196. Table 3.3: Overall IVD Testing Market Worldwide, 2007 20
  197. Table 3.4: Worldwide Distribution of IVD Testing, 2007 20
  198. Table 3.5: Top 12 Countries for IVD Testing Markets, 2007 20
  199. Table 3.6: Eight Largest Diagnostic Companies Worldwide, 2007 21
  200. Table 3.7: Cardiac Markers 23
  201. Table 3.8: Market Share of Cardiac Marker Segment 26
  202. Table 3.9: U.S. Cardiac Marker Market, 2001-2010 27
  203. Table 3.10: U.S. Cardiac Marker Diagnostic Testing Market Segments, 2007 27
  204. Table 3.11: U.S. POC Cardiac Marker Sales, 2001-2010 28
  205. Table 3.12: The Cardiac Marker Market for Diagnostic Testing in Europe, 2001-2010 30
  206. Table 3.13: Regional Comparison of Healthcare and IVD Expenditures 31
  207. Table 3.14: German Diagnostics Products Market Sales, 1997-2008 32
  208. Table 3.15: The German Cardiac Marker Test Market, 2000-2010 32
  209. Table 3.16: U.K. Cardiac Marker Market, 2001-2010 34
  210. Table 3.17: Major U.K. IVD Manufacturers 34
  211. Table 3.18: U.S. IVD Manufacturers Doing Business in the U.K. 34
  212. Table 3.19: Other European Companies that Manufacture IVD Products in the U.K. 35
  213. Table 3.20: Italian Cardiac Marker Market, 2001-2010 35
  214. Table 3.21: French Cardiac Marker Market, 2001-2010 36
  215. Table 3.22: Spanish Cardiac Marker Market, 2001-2010 36
  216. Table 3.23: Japanese Cardiac Marker Diagnostic Testing Market, 2001-2010 37
  217. Table 3.24: Chinese Diagnostics Products Market, 2000-2010 38
  218. Table 3.25: ER Admissions in the U.S., 1997-2005 43
  219. Table 3.26: Common Causes of Chest Pain 43
  220. Table 3.27: Rate of Inappropriate Discharge from the ER for Patients with AMI 44
  221. Table 3.28: Continuing Analytical Issues for Implementation of Cardiac Troponin 46
  222. Table 3.29: Global Cardiac Troponin Marker Market, 2001-2010 47
  223. Table 3.30: U.S. Cardiac Troponin Marker Market, 2001-2010 48
  224. Table 3.31: Trends in U.S. Sales of POC Cardiac Marker Tests, 1998-2007 48
  225. Table 3.32: World Revenue from CK-MB Markets, 2001-2010 53
  226. Table 3.33: U.S. Revenue from CK-MB Markets, 2001-2010 53
  227. Table 3.34: World Myoglobin Market Revenues, 2001-2010 54
  228. Table 3.35: U.S. Myoglobin Market Revenues, 2001-2010 55
  229. Table 3.36: BNP Clinical Characteristics 57
  230. Table 3.37: Worldwide Sales of BNP Diagnostic Tests, 2004-2010 58
  231. Table 3.38: U.S. Sales of BNP Diagnostic Tests, 2004-2010 58
  232. Table 3.39: Commercial BNP Assays in the U.S. 61
  233. Table 3.40: Market Share of BNP Assays in the U.S. 61
  234. Table 3.41: Market Share of NT-proBNP Assays in the U.S. 61
  235. Table 3.42: Siemens Healthcare Diagnostics Cardiac Marker Assays 76
  236. Table 3.43: Cardiac Markers: Sampling Frequency 77
  237. Table 3.44: Cardiac Marker Products by LifeSign 80
  238. Table 4.1: HDL Levels in Adults 86
  239. Table 4.2: LDL Levels in Adults 87
  240. Table 4.3: LDL Screening Management Rates-Percent of Patient Population 87
  241. Table 4.4: Number of U.S. Cholesterol Tests, 2000-2010 88
  242. Table 4.5: World CRP Market Revenue, 2001-2010 90
  243. Table 4.6: U.S. CRP Market Revenue, 2001-2010 91
  244. Table 4.7: Clinical Characteristics of D-Dimer 92
  245. Table 5.1: POCT in Two Hospitals Cost Analysis with Labor Included 102
  246. Table 5.2: Cost Analysis for Glucose Testing: POCT vs. Central Lab 102
  247. Table 5.3: Financial Comparison for Moderate and Waived CLIA Labs 103
  248. Table 5.4: POCT Clinical Outcomes in AMI 105
  249. Table 7.1: Oxidative Biomarker Research Assay Market Size 123
  250. Table 7.2: Non-Lipid Markers of CVD 127
  251. Table 8.1: Products Marketed by Abbott in the Diagnostic Market 135
  252. Table 8.2: Products Marketed by Biosite in the Diagnostic Market 143

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